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From Iran to North Korea, from the New START treaty to Syria's deadly chemical stockpile, nuclear, chemical, and biological weapons are the focus of high politics around the world. Decisions about them can make the difference between war and peace, between safety and grave danger for people around the world. This course will give students an understanding of these weapons and the global efforts to control their spread and reduce their dangers. The course covers policy tools from treaties and diplomacy to sanctions and war. Students will learn to use an integrated risk-informed approach to assessing policy options when difficult choices need to be made in the face of large uncertainties. This will prepare them for careers dealing with choices about these deadly weapons.