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The United States and Russia currently possess more than 90% of the world's nuclear weapons. Once the United States and Russia eventually resume the long-term trend of reducing their nuclear forces, the relative proportion of nuclear capability represented by the five other recognized nuclear weapon states (China, France, United Kingdom, India, and Pakistan) will increase. The shift from a bipolar to a multipolar nuclear system means that nuclear developments in any one of the nuclear-armed states can have a cascading effect that ultimately impacts the rest of the system. Officials in both the United States and Russia have stated that future nuclear reduction talks will eventually need to involve the other nuclear-armed states in some form or fashion. Multilateral strategic nuclear arms control, however, is uncharted territory. What are the prospects of including the other nuclear-armed states in future strategic arms control negotiations? What are the most important obstacles to such negotiations? What measures short of formal negotiations could nuclear-armed states implement to enhance strategic stability? What steps could the United States take, on its own or in conjunction with other nuclear weapon states, in the near-term to facilitate the eventual transition from bilateral to multilateral nuclear arms control?