Diagnostic Microbiology and Infectious Disease
Vol. 109, Issue 3
Date of Publication: July 2024

Authors:

  • Phyllis Kanki
This study evaluates the effects of freeze-thaw cycles on the viability of SARS-CoV-2 samples used for live virus culture. The authors investigate how sample handling and storage conditions influence viral recovery and laboratory diagnostic reliability. Findings provide important guidance for clinical laboratories and infectious disease researchers regarding specimen preservation, biosafety procedures, and the interpretation of virological testing results during SARS-CoV-2 surveillance and research.

Citations

Kanki PJ, Hamel DJ, Riedel S, Dutta S, Cheng A, Chang CA, Arnaout R, Kirby JE. SARS-CoV-2 live virus culture and sample freeze-thaw stability. Diagn Microbiol Infect Dis. 2024 Jul;109(3):116282. doi:10.1016/j.diagmicrobio.2024.116282.