At the time of its establishment in 2004, the Corporate Responsibility Initiative (CRI) was supported by four core funders:  Walter H. Shorenstein, Chevron Corporation, The Coca-Cola Company and General Motors. 

Over the past two decades, in addition to ongoing support from its initial four donors, the initiative has received funding from a variety of other companies, foundations and government or intergovernmental agencies. These have included (in alphabetical order): Abbott; AbbVie; Bill & Melinda Gates Foundation; Business Fights Poverty; Cisco Systems; Endeva; ExxonMobil; General Electric (GE); InterContinental Hotels Group (IHG); International Bar Association; Microsoft; Nestlé; Pfizer; SABMiller (now ABInBev); SAP; Shell; Unilever; Yara; the United Kingdom Department for International Development (DFID); the World Economic Forum; and various United Nations organizations.

Over the same period, CRI has co-hosted events and undertaken projects with Business Fights Poverty; Ceres; FSG; the Global Alliance for Improved Nutrition (GAIN); Shift; the World Bank Group; the World Economic Forum; and the United Nations. The latter has included engagement with the Office of the United Nations High Commissioner for Human Rights (OHCHR); the United Nations Industrial Development Organization (UNIDO), the United Nations Development Programme (UNDP), the United Nations Environment Programme (UNEP), the Joint United Nations Programme on HIV/AIDS (UNAIDS); the World Health Organization (WHO); and the United Nations Global Compact.