This course examines public policies for urban and regional economic development. Cities are the growth engines of modern economies. They attract workers seeking jobs, firms pursuing access to markets, consumers wanting an abundant variety of goods and services, and individuals and families desiring access to public services, attractive places to live, and a sense of community. Urban density confers economic benefits by allowing cities to supply public services more efficiently, making workers more productive on the job, and providing individuals with opportunities for novel pursuits. Yet, urban residents must contend with traffic congestion, expensive housing, pollution, crime, unequal access to opportunity, and disease exposure. Alongside larger cities, smaller towns and rural communities play vital economic roles, often by leveraging their natural resources. Competition among regions for capital, labor, and public resources creates a hierarchy of places in which there tend to be a few large cities, many small cities, and inequality within and between places. Technological change, global competition, climate shocks, and government policy continually perturb economic geographies, moving regions up and down the ladder of prosperity. By the end of the course, students will understand the economic forces that drive urban and regional growth, induce industries to concentrate geographically, and determine why some communities flourish and others do not. They will also understand the economics of policies on affordable housing, public infrastructure, urban sprawl, traffic congestion, productivity growth, regional economic distress, and climate change. The course involves traditional lectures, in-class case studies, and policy debates. About 60% of course material relates to the US and about 40% is international. The course uses insights and data from the Reimagining the Economy Project and the Economy in Place data viz platform.