Background: Recent evidence suggests that individual variation in risk taking is partly due to genetic factors. Methodology/Principal Findings: We explore how self-reported risk taking in different domains correlates with variation in the dopamine receptor D4 gene (DRD4). Past studies conflict on the influence of DRD4 in relation to risk taking. A sample of 237 serious tournament contract bridge players, experts on risk taking in one domain, was genotyped for having a 7-repeat allele (7R+) or not (7R-) at DRD4. No difference was found between 7R+ and 7R- individuals in general risk taking or in several other risk-related activities. Conclusion: In this sample of individuals (tournament bridge players) there is no relationship between DRD4 genotype and self-reported risk taking in different domains.
Dreber, Anna, David G. Rand, Nils Wernerfelt, Justin R. Garcia, J. Koji Lum, and Richard Zeckhauser. "The Dopamine Receptor D4 Gene (DRD4) and Self-Reported Risk Taking in the Economic Domain." HKS Faculty Research Working Paper Series RWP11-042, November 2011.