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Abstract

This retrospective study analyzed glycemic trends, incidence of post-transplant diabetes mellitus (PTDM) incidence and associated risk factors in a cohort of patients who underwent first-time heart transplantation (HT). Univariate analyses compared patient with and without pretransplant diabetes mellitus (DM). Multivariate regression analyses were conducted to determine association between PTDM and different risk factors. Finally, trends in glucometrics and other outcomes are described across follow-up time points. There were 152 patients who underwent HT between 2010 and 2015, 109 of whom had no pretransplant history of DM. PTDM incidence was 38% by the 1-year follow-up. Pretransplant body mass index (odds ratio [OR] 1.12, 95% confidence interval [CI] 1.01 to 1.23, p?=?0.03), insulin use during the final 24 hours of inpatient stay (OR 4.26, 95% CI 1.72 to 10.56, p

Citation

Munshi, Vidit N., Soroush Saghafian, Curtiss B. Cook, Eric Steidley, Brian Hardaway, and Harini A. Chakkera. "Incidence, Risk Factors, and Trends for Postheart Transplantation Diabetes Mellitus." The American Journal of Cardiology 125.3 (February 2020): 436-440.